Dr John r Christopher knew that Cascara is an aperient, a laxative which works gently and without griping or irritation to produce easier evacuation and normal stool function colon cleansing, colon health, herbal remedies for colon health. It acts specifically upon the large intestines, which gives it its importance in the lower bowel formula (cleansing of the lower bowel). It is recommended for cases of long-standing constipation, used in small doses over a long period of time. Even if an immediate effect does not take place, eventually the Cascara will tone and strengthen the bowel and effect normal function. Therefore, if you are looking for a strong, one- time laxative, choose Turkey Rhubarb or some other cathartic, instead of Cascara Sagrada. Cascara acts wonderfully to tone the entire alimentary canal, increasing the secretions of the stomach, liver, pancreas and lower bowels. It is also most beneficial to the gall ducts, and relieves liver complaints, especially enlarged liver. 100% vegetarian capsules.